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Welcome to AnemiaAlert
Thank you for signing
up for AnemiaAlert, the e-newsletter of the National Anemia
Action Council. NAAC’s bimonthly e-newsletter
responds to the need of health care professionals for timely,
quick-to-read information on anemia.
Each issue
contains facts from recent research that may impact your practice.
You are also able to quickly link to www.anemia.org,
NAAC's Web site, to read features, which include interviews
with leading anemia researchers and commentaries by NAAC specialists,
and to review expert answers to submitted practice questions.
Be sure to access the Web site's newest
features: NAAC’s
free electronic CME courses and The
NAAC Anemia Reference Library.
Fast Facts
RHuEPO
Crosses the Blood-Brain Barrier
A study of the pharmacokinetics of recombinant human erythropoietin
(rHuEPO) in the serum and cerebrospinal fluid of four patients
indicates that rHuEPO does cross the blood-brain barrier
after intravenous administration. Although rHuEPO has been
demonstrated to be neuroprotective in experimental brain
injury studies, clinical trials are required to determine
if this translates into improved patient outcomes.
(Presented by A. Xenocostas et al, London Health Sciences
Centre, Toronto, Canada, at ASCO, 2003, Abstract No. 922.)
Androgen
Deprivation Plus Radiation Increases Anemia in Prostate Cancer
Patients
Results of a retrospective study of 172 patients indicate
that the addition of androgen deprivation therapy to curative-intent
radiation therapy increases the prevalence and severity of
anemia in prostate cancer patients and is more pronounced
in patients who are already anemic.
(Presented by L. B. Harrison et al, Beth Israel Medical Center,
New York, NY, at ASCO, 2003, Abstract No. 3024.)
Combined
Nephrology and Cardiology Care Effective for Patients With
CHF and CKD
A review of the care of 179 patients at Tel Aviv Medical
Center reveals that joint nephrology-cardiology care for
patients with resistant congestive heart failure (CHF) and
chronic kidney disease (CKD) has generally resulted in improved
hemoglobin levels, serum creatinine levels, New York Heart
Association status, and quality of life scores; less dyspnea
and fatigue; and lessened need for hospitalization or furosemide.
The authors suggest that such cooperative care in which CHF
is aggressively treated and anemia is controlled may prevent
deterioration of both CHF and CKD.
(Blood Purif. 2003;21:124-130.)
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Some
Anemia May Be Attributed to Aging
Although anemia in the elderly is often attributed to chronic
disease or iron deficiency, in about 20% of these patients
the cause remains unknown. These cases may be associated
with the increased production of proinflammatory cytokines,
such as interleukin-6, which occurs with age even if no chronic
disease or inflammation is present.
(J Am Geriatr Soc. 2003;51:S18-S21.)
What's New at
www.anemia.org
Featured Research With
topics selected by the NAAC leadership, these articles include
interviews with leading anemia researchers, often accompanied
by commentaries written by NAAC specialists. The latest postings:
Perioperative
Anemia Requires Careful Evaluation and Treatment
Anemia Increases
Risk of Progression of Chronic Renal Failure
Death and
Rehospitalization Rates Higher in Older Heart Failure Patients
With Anemia
Research Briefs These
annotated summaries highlight other important recent research.
The latest postings:
Height Not
the Only Growth Parameter Affected by Iron Deficiency Anemia
Anemia
Has Medical, Functional Consequences in Older Patients
Questionnaire
Detects Anemia in Gastroenterology Outpatients
Nurses Urged
to Help Maintain Hemoglobin in Patients With Chronic Kidney
Disease
Answers
to Your Practice Questions
NAAC
specialists respond to practice questions submitted by physicians
and other health care professionals. The latest postings:
Is surgery
not advised with a hemoglobin of 9.7g/dL and if so, why?
Is
iron supplementation (PO or IV) required when the hematocrit
has achieved the target (36%-38%) in dialysis patients receiving
erythropoietin?
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Free
E-CME |
Now you can
conveniently update your anemia knowledge and simultaneously
meet CME requirements at www.anemia.org.
Complete the course and print
your certificate—all within 1 hour. The
Free E-CME Courses
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The
NAAC Anemia Reference Library |
The NAAC
Anemia Reference Library is a comprehensive online resource
for research
on secondary anemias. Searchable
by category, most references are linked to a National Library
of Medicine PubMed abstract or an associated Web site. The
database is continually updated with the latest published anemia
studies. The
NAAC Anemia Reference Library NAAC
is supported by an unrestricted educational grant from
Amgen Inc.

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